Coffee may be able to block inflammation+ details

Coffee contains active compounds with antioxidant and anti-inflammatory properties that may help reduce low grade inflammation and protect against certain diseases.

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Coffee is one of the most consumed beverages worldwide. It’s rich in an array of beneficial compounds that may help maintain optimal health and protect you from certain diseases (1Trusted Source).

Coffee is also thought to help reduce inflammation, at least in some people.

This article reviews coffee’s effects on inflammation, as well as whether decaffeinated coffee has the same effects.



Contains a complex mixture of active compounds

Regular coffee contains a complex mixture of active compounds, including caffeine, chlorogenic acid (CGA), cafestol, trigonelline, and kahweol. Decaffeinated coffee contains the same compounds, although it contains little to no caffeine (1Trusted Source2).

Studies suggest that the compounds in coffee have potent antioxidant and anti-inflammatory properties that likely benefit your health (1Trusted Source2).

Experts believe that their presence may explain why drinking coffee — whether it’s regular or decaf — is often linked to a lower risk of illnesses, such as type 2 diabetes, heart disease, and possibly even certain types of cancer (1Trusted Source3Trusted Source).



Effects on inflammation

Current research suggests that coffee may help reduce inflammation, at least in certain individuals.

In one study, regular coffee drinkers had lower levels of inflammatory markers than non-regular coffee drinkers (4Trusted Source).

In another study, regular coffee drinkers experienced a 6% increase in their inflammatory marker levels when asked to refrain from drinking coffee for 1 month.

Health Benefits of Coffee, Based on Science+detail


In comparison, they experienced an 8–16% reduction in inflammatory markers when asked to consume either 32 or 64 ounces (0.9 or 1.9 liters) of coffee per day for the same time period (5Trusted Source).

What’s more, a review of 15 studies on the effects of coffee, caffeine, and other coffee-related components on inflammatory markers found that low, medium, and high coffee intake has predominantly anti-inflammatory effects (3Trusted Source).


Nevertheless, some evidence suggests that coffee may increase inflammation in some people. Therefore, individual differences in genetics or other factors likely influence coffee’s effect on inflammation (3Trusted Source6Trusted Source).

Inflammation can lead to a variety of effects, including frequent infections, fatigue, pain, and digestive problems. If you experience any of these while drinking coffee, consider reducing your intake to see whether doing so helps (7Trusted Source).






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