lionel Messi has tested negative for Covid-19 and is now back in France and will resume training "in the coming days," Paris Saint-Germain announced on Wednesday.
The seven-time Ballon d'Or winner tested positive for the virus while in his native Argentina last week but flew back to Paris on Wednesday.
He missed PSG's 4-0 French Cup win against Vannes on Monday.
The club did not say if Messi would be available for their first Ligue 1 match since the winter break, at Lyon on Sunday.
"The test carried out by Leo Messi was negative for Covid-19. He has arrived in Paris and he will resume with the group in the coming days," PSG said in a statement.
Messi has endured a difficult start to life in the French capital since an emotional exit from Barcelona last summer.
He has scored only one goal in 11 league appearances for PSG, although he has netted five times in the Champions League.
The French capital giants also said that full-back Layvin Kurzawa had tested positive for Covid on Wednesday and was in self-isolation.
Goalkeeper Gianluigi Donnarumma, defender Juan Bernat, back-up keeper Sergio Rico, midfielder Danilo Pereira and teenager Nathan Bitumazala have all also returned positive Covid test results in the past week.
Lionel Messi's posetive covid-19
Paris Saint-Germain have offered a short update confirming Lionel Messi - along with team-mates Juan Bernat, Sergio Rico and Nathan Bitumazala have tested positive for Covid-19
Messi has endured an up and down start to life in PSG, having shocked the football world by leaving Barcelona in the summer.
The Argentinian star has endured a difficult start to life in the French capital since an emotional exit from Barcelona last summer.
Messi has scored only one goal in 11 league appearances for PSG, although he has netted five times in the Champions League.
He will miss Monday's cup tie and will likely also be sidelined for PSG's first Ligue 1 match since the winter break, at Lyon next Sunday.
In the domestic league Messi has managed just one goal, although he has been prolific in Europe scoring five in as many Champions League fixtures.
He did play in PSG’s final game before the Christmas break, but is now set for a spell on the sidelines.
In a short statement on the club’s site, PSG said: “The medical update for this Sunday, January 2 concerns Leo Messi, Juan Bernat, Sergio Rico, Nathan Bitumazala and Neymar Jr.
“The 4 positive players for Covid-19 are Leo Messi , Juan Bernat , Sergio Rico and Nathan Bitumazala . They currently respect isolation and are subject to the appropriate health protocol.
“Neymar JR will continue his care in Brazil until January 9 with members of the medical and performance staff of Paris Saint-Germain. His return to training is still expected in about 3 weeks.”
“I can only give thanks for everything that I had to live in this 2021,” he wrote. “'Even more so when many people had a really bad time because of the s***** virus that never ends.
“Hopefully 2022 brings a lot of health, which is what I wish you all for the new year. Hug everyone!”
Following the game with fourth-tier Vannes, PSG are set to face-off against Lyon on Sunday night, as they look to extend their mammoth 13-point gap at the top of Ligue 1.
The number of Covid cases in France has topped 200,000 a day this week.
Barcelona left frustrated after club ambassador Ronaldinho admitted that Lionel Messi's move to Paris Saint-Germain was 'a pleasant surprise'
Barcelona have been left disappointed by comments made by club ambassador Ronaldinho regarding Lionel Messi's move to Paris Saint-Germain.
Messi ended his lengthy association with Barcelona last summer when he joined PSG on a free transfer, with Ronaldinho commenting that the deal was 'a pleasant surprise'.
Ronaldinho played for PSG between 2001 and 2003 before signing for Barcelona.